Publications
2025
T Hui#, J Zhou#, M Yao, Y Xie, H Zeng*. Advances in spatial omics technologies. Small Methods (2025), e2401171. (Review)get the PDF
D Bai#, J Yang#, X Xue#, Y Gao#, Y Wang, M Cui, B He, H Zeng, H Xiang, Z Guo, L Zhu, J Gao, C Zhu*, F Tang*, C Yi*. Single-cell 5-hydroxymethylcytosine landscapes of mouse early embryos at single-base resolution. Cell Rep. (2025) 44, 115520. get the PDF
2024
Z Tang#, S Luo#, H Zeng, J Huang, X Sui, M Wu, X Wang*. Search and match across spatial omics samples at single-cell resolution. Nat. Methods (2024) 21, 1818–1829. get the PDF
2023
H Zeng#, J Huang#, J Ren#, C K Wang, Z Tang, H Zhou, Y Zhou, H Shi, A Aditham, X Sui, H Chen, J A Lo, X Wang*. Spatially Resolved single-cell translatomics at molecular resolution. Science (2023) 380, eadd3067. (Highlighted in the Nature Reviews Genetics and Nature Methods ).get the PDF
J Ren#, H Zhou#, H Zeng#, C K Wang, J Huang, X Qiu, X Sui, Q Li, X Wu, Z Lin, J A Lo, K Maher, Y He, X Tang, J Lam, H Chen, B Li, D E Fisher, J Liu, X Wang*. Spatiotemporally resolved transcriptomics reveals the subcellular RNA kinetic landscape. Nat. Methods (2023) 20, 695–705. get the PDF
H Zeng#, J Huang#, H Zhou#, W J. Meilandt, B Dejanovic, Y Zhou, C J. Bohlen, S Lee, J Ren, A Liu, Z Tang, H Sheng, J Liu, M Sheng *, X Wang*. Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer’s disease. Nat. Neurosci. (2023) 26, 430–446.get the PDF
Before 2023
B He#, C Zhang#, X Zhang#, Y Fan#, H Zeng, J Liu, H Meng, D Bai, J Peng, Q Zhang*, W Tao*, C Yi*. Tissue-specific 5-hydroxymethylcytosine landscape of the human genome. Nat. Commun. (2021) 12:4249.get the PDF
M Liu#, J Zhang#, C Zhu#, X Zhang, W Xiao, Y Yan, L Liu, H Zeng, YQ Gao*, C Yi*. DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes. Nat. Commun. (2021) 12:4108.get the PDF
A Aditham#, H Shi#, J Guo, H Zeng, Y Zhou, S D Wade, J Huang, J Liu, X Wang*. Chemically modified mocRNAs for highly efficient protein expression in mammalian cells. ACS Chem. Biol. (2022) 17, 3352-3366.get the PDF
H Zeng#, M Mondal#, R Song#, J Zhang, B Xia, M Liu, C Zhu, B He, YQ Gao* and C Yi*. Unnatural cytosine bases recognized as thymines by DNA polymerases via the formation of the Watson-Crick geometry. Angew. Chem. Int. Ed. (2019) 58, 130-133.get the PDF
H Zeng#, B He#, C Yi*. Compilation of modern technologies to map genome-wide cytosine modifications in DNA. Chembiochem (2019) 20, 1898-1905.(Review)get the PDF
H Zeng#, B He#, B Xia, D Bai, X Lu, J Cai, L Chen, A Zhou, C Zhu, H Meng, Y Gao, H Guo, C He*, Q Dai*, and C Yi*. Bisulfite-Free, Nanoscale Analysis of 5-Hydroxymethylcytosine at Single Base Resolution. J. Am. Chem. Soc. (2018) 140, 13190-13194.get the PDF
H Zeng#, B He#, C Yi*, and J Peng*. Liquid biopsies: DNA methylation analyses in circulating cell-free DNA. J. Genet. Genomics (2018) 45, 185-192. (Review)get the PDF
C Zhu#, Y Gao#, H Guo#, B Xia#, J Song, X Wu, H Zeng, K Kee, F Tang*, and C Yi*. Single-Cell 5-Formylcytosine Landscapes of Mammalian Early Embryos and ESCs at Single-Base Resolution. Cell Stem Cell (2017) 20, 720-731 e725.get the PDF
B Xia#, D Han#, X Lu#, Z Sun, A Zhou, Q Yin, H Zeng, M Liu, X Jiang, W Xie, C He*, and C Yi*. Bisulfite-free, base-resolution analysis of 5-formylcytosine at the genome scale. Nat. Methods (2015) 12, 1047-1050.get the PDF